Opportunity Information: Apply for RFA DA 21 029
The HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR) opportunity (RFA-DA-21-029) is an NIH grant that funds a single Coordination and Dissemination Center to support a broader IMPOWR research network made up of multiple clinical research centers. The overall goal is to strengthen and organize multidisciplinary, team-based research focused on people with complex clinical needs: chronic pain alongside opioid use disorder (OUD) or opioid misuse. By creating a coordinated network, NIH is aiming to speed the development, testing, and real-world uptake of interventions and care approaches that can improve both pain outcomes and addiction-related outcomes, rather than treating them in isolation.
This Coordination and Dissemination Center is meant to serve as the hub that keeps the network functioning as a unified effort. In practical terms, that kind of center typically provides the operational backbone for multi-site work: coordinating collaboration across participating clinical research centers, supporting shared processes and standards, helping manage communication and data harmonization across studies, and ensuring that findings and best practices are packaged and shared in ways that actually reach clinicians, health systems, and other decision-makers. The emphasis on dissemination highlights that NIH is not only interested in generating knowledge, but also in making sure successful models of care and implementation strategies can be adopted and sustained in real settings where patients receive care.
The IMPOWR network sits within the NIH Helping to End Addiction Long-term (HEAL) Initiative, which is NIH's large, cross-agency effort to accelerate scientific solutions to the opioid public health crisis. HEAL has two major research thrusts that show up clearly in this funding announcement: improving prevention and treatment for opioid misuse and OUD, and enhancing pain management. IMPOWR targets the overlap of these areas by focusing on integrative management and whole-person recovery, reflecting the reality that chronic pain and opioid-related problems often interact and can complicate treatment planning, engagement, and long-term outcomes.
The funding mechanism is an R24 (clinical trial optional), meaning the award is structured to support resources, infrastructure, and coordination activities that enable clinical research and its translation, rather than funding a standalone clinical trial as the only core purpose (though clinical trial-related activities may be allowable depending on the application). NIH expects to make one award under this opportunity, with an award ceiling of $575,000. The opportunity was posted January 11, 2021, with an original closing date of March 31, 2021, indicating a time-limited competition intended to quickly stand up the coordinating function for the network.
Eligibility is broad and includes many organization types that could credibly serve as a national coordinating hub: state, county, and local governments; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; nonprofits with or without 501(c)(3) status; public housing authorities/Indian housing authorities; for-profit organizations (other than small businesses) as well as small businesses; and other entities as allowed by NIH's additional eligibility language. The awarding agency is the Department of Health and Human Services, National Institutes of Health, and the opportunity is associated with multiple CFDA numbers (93.213, 93.242, 93.273, 93.279, 93.846), reflecting NIH's multi-institute involvement and the cross-cutting nature of pain and addiction research.Apply for RFA DA 21 029
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Coordination and Dissemination Center (R24 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.242, 93.273, 93.279, 93.846.
- This funding opportunity was created on Jan 11, 2021.
- Applicants must submit their applications by Mar 31, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $575,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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