Supplements for Validating the Use of Automated Sources of Residential Histories in Cancer Epidemiology Cohorts (Admin Supp) | PA 17 222

Opportunity Information: Apply for PA 17 222

The National Cancer Institute (NCI), under the National Institutes of Health (NIH), issued an administrative supplement opportunity titled "Supplements for Validating the Use of Automated Sources of Residential Histories in Cancer Epidemiology Cohorts (Admin Supp)" (Funding Opportunity Number PA-17-222). The purpose of this supplement is to provide additional, limited funding to investigators who already hold eligible NCI-funded awards so they can expand or accelerate work that improves how lifetime residential histories are captured for participants in cancer epidemiology cohorts. In practical terms, NCI is looking to strengthen the accuracy and reliability of residential address histories that are assembled through automated methods, and to improve the linkages that depend on those address histories, because residential location over time is often central to studying environmental, neighborhood, and place-based contributors to cancer risk and outcomes.

This opportunity focuses on refining and validating automated sources and approaches used to construct residential histories. Cancer epidemiology studies frequently need detailed, time-resolved address data across a person’s life to support exposure assessment (for example, linking people to air pollution estimates, drinking water sources, pesticide applications, industrial emissions, traffic-related exposures, neighborhood socioeconomic conditions, or other geographically varying factors). Traditional collection of residential history can be costly and error-prone when it relies entirely on participant recall or manual record abstraction. Automated sources, such as administrative databases or commercial address histories, can potentially fill gaps and reduce burden, but they also introduce concerns about completeness, timing, geocoding accuracy, misclassification, and differential performance across populations. The supplement funding is intended to support added efforts that test, verify, and improve these automated pipelines so that downstream cancer research analyses are based on higher-quality location data.

The mechanism is an administrative supplement, meaning it is not a stand-alone new research grant for a brand-new project; it is additional funding that must be requested by an organization with an active, eligible NCI award and the proposed activities must be within the scope of that parent award. The announcement is categorized as a discretionary grant opportunity in the Education and Health activity area, associated with CFDA number 93.399. The posted award ceiling is $125,000, indicating the maximum supplement amount per award under this announcement (with the actual amount dependent on the specific request and NCI approval).

A broad range of U.S.-based applicant organizations are listed as eligible, reflecting NIH’s typical eligibility framework for research-related funding. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; certain tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights several institution types and community-oriented entities as eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the opportunity places clear limits on foreign participation. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply for this supplement. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In other words, the supplement work must be carried out within allowable U.S.-based organizational structures without foreign components.

Key administrative details in the source listing include an original closing date of 2017-06-01 and a creation date of 2017-03-14. While the listing does not specify the number of expected awards, the overall intent is straightforward: enable existing NCI-funded teams to add targeted validation and improvement work around automated residential history data sources and their linkage methods, so that epidemiologic cohorts can more confidently connect residential location over time to exposures and contextual factors relevant to cancer etiology, survivorship, and outcomes.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Supplements for Validating the Use of Automated Sources of Residential Histories in Cancer Epidemiology Cohorts (Admin Supp)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399.
• This funding opportunity was created on 2017-03-14.
• Applicants must submit their applications by 2017-06-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $125,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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