Opportunity Information: Apply for PAR 19 371
The NIAID Career Transition Award (K22, Independent Clinical Trial Not Allowed) is a National Institutes of Health grant opportunity intended to help postdoctoral fellows make the jump into independent faculty-level research careers. Its core goal is career development: supporting researchers as they move into an assistant professor position (or an equivalent role) and begin establishing themselves as independent biomedical scientists. In practice, this mechanism is meant to provide structured support at a key inflection point, when a postdoc is building a distinct research niche, demonstrating independence from mentors, and laying the groundwork for a long-term research program.
A central feature of this specific Funding Opportunity Announcement is the restriction on clinical trials. It is designed for applicants whose proposed research will not include leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. That said, the announcement does allow an applicant to gain experience on a clinical trial as long as the trial is led by a mentor or co-mentor. In other words, clinical trial exposure is allowed in a training or mentored capacity, but the K22-supported candidate cannot be the person directing an independent clinical trial effort under this FOA.
The opportunity is administered by the National Institutes of Health under a discretionary grant funding instrument, with a health-focused funding activity category and CFDA number 93.855. The funding opportunity title is "NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)," and the opportunity number is PAR-19-371. The record lists a creation date of September 9, 2019, and an original closing date of January 7, 2022, reflecting the posted window for applications under this announcement.
Eligibility spans a wide range of organization types, reflecting the NIH’s broad applicant landscape. Eligible applicants include many public-sector entities (such as state governments, county governments, city or township governments, special district governments, and independent school districts), as well as public and state-controlled institutions of higher education and private institutions of higher education. Tribal eligibility is also included, covering federally recognized Native American tribal governments, as well as Native American tribal organizations and certain tribal governments that are not federally recognized. The announcement also lists public housing authorities/Indian housing authorities, nonprofit organizations (both 501(c)(3) and nonprofits without 501(c)(3) status, in both cases other than institutions of higher education), for-profit organizations other than small businesses, and small businesses, along with an "Other" category.
The FOA additionally highlights categories of "other eligible applicants" that commonly reflect federally recognized institution types and community-serving entities. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, and faith-based or community-based organizations. It also references regional organizations and U.S. territories or possessions as eligible categories.
At the same time, the announcement is explicit about restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply. Non-domestic components of U.S. organizations are not eligible to apply, and foreign components, as defined by the NIH Grants Policy Statement, are not allowed. The net effect is that the applicant organization and project components must be fully domestic under NIH rules for this specific opportunity.
Overall, this K22 is best understood as a career transition mechanism: it is aimed at helping postdoctoral researchers move into independent positions and start building a sustainable research program, while drawing a clear boundary around the kinds of clinical trial leadership activities that can and cannot be proposed under this particular "independent clinical trial not allowed" version of the award.Apply for PAR 19 371
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
- This funding opportunity was created on 2019-09-09.
- Applicants must submit their applications by 2022-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the NIAID Career Transition Award (K22, Independent Clinical Trial Not Allowed)?
The NIAID Career Transition Award (K22, Independent Clinical Trial Not Allowed) is a National Institutes of Health (NIH) grant opportunity intended to help postdoctoral fellows transition into independent, faculty-level research careers. It is designed to support researchers as they move into an assistant professor position (or an equivalent role) and begin establishing themselves as independent biomedical scientists.
What is the primary purpose of this K22 opportunity?
The core purpose is career development during a key transition point from postdoctoral training to independence. The award is meant to provide structured support while the candidate develops a distinct research niche, demonstrates independence from mentors, and lays the groundwork for a long-term research program.
Who is this award intended for?
This mechanism is intended for postdoctoral fellows who are preparing to make the jump to an independent position, such as an assistant professor role (or an equivalent position), and who are working to establish themselves as independent biomedical researchers.
What does "Independent Clinical Trial Not Allowed" mean for this FOA?
It means the proposed research under this Funding Opportunity Announcement (FOA) cannot include leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. In this FOA, the K22-supported candidate cannot be the person directing an independent clinical trial effort.
Are any clinical trial activities allowed under this K22?
Yes. The FOA allows the applicant to gain experience on a clinical trial as long as the trial is led by a mentor or co-mentor. Clinical trial exposure is allowed in a training or mentored capacity, but the candidate cannot lead an independent clinical trial under this announcement.
Which NIH institute administers this opportunity?
This opportunity is administered by the National Institutes of Health (NIH). The FOA is titled "NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)," indicating it is associated with NIAID.
What is the opportunity number for this FOA?
The opportunity number is PAR-19-371.
What is the CFDA number associated with this grant opportunity?
The CFDA number listed for this opportunity is 93.855.
What type of funding instrument is used?
The FOA is administered under a discretionary grant funding instrument.
What is the funding activity category?
The funding activity category is health-focused.
When was this opportunity created?
The record lists a creation date of September 9, 2019.
What is the original closing date shown for this FOA?
The record lists an original closing date of January 7, 2022, reflecting the posted window for applications under this announcement.
What types of organizations are eligible to apply?
Eligibility includes a wide range of organization types commonly eligible for NIH opportunities, including public-sector entities, institutions of higher education, tribal entities and organizations, nonprofits, for-profits, small businesses, and additional listed categories (such as certain community-serving entities and U.S. territories or possessions).
Are state, county, and local governments eligible applicants?
Yes. Eligible applicants include state governments, county governments, city or township governments, special district governments, and independent school districts.
Are institutions of higher education eligible?
Yes. The FOA lists public and state-controlled institutions of higher education as eligible, as well as private institutions of higher education.
Are tribal governments and tribal organizations eligible to apply?
Yes. The FOA includes federally recognized Native American tribal governments as eligible. It also lists Native American tribal organizations and certain tribal governments that are not federally recognized.
Are nonprofit organizations eligible?
Yes. The FOA lists nonprofit organizations with 501(c)(3) status (other than institutions of higher education) and nonprofits without 501(c)(3) status (other than institutions of higher education).
Are for-profit organizations eligible?
Yes. The FOA lists for-profit organizations other than small businesses, as well as small businesses, as eligible applicants.
Are public housing authorities eligible to apply?
Yes. The FOA lists public housing authorities/Indian housing authorities as eligible applicants.
What are the "other eligible applicants" mentioned in the announcement?
The FOA highlights additional categories that commonly reflect federally recognized institution types and community-serving entities. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, and faith-based or community-based organizations. It also references regional organizations and U.S. territories or possessions.
Are U.S. territories or possessions eligible?
Yes. The FOA references U.S. territories or possessions as eligible categories.
Are foreign (non-U.S.) organizations eligible to apply?
No. The FOA explicitly states that non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply.
Can a U.S. organization apply if part of the project is conducted outside the United States?
No. The FOA states that non-domestic components of U.S. organizations are not eligible to apply and that foreign components (as defined by the NIH Grants Policy Statement) are not allowed. The applicant organization and project components must be fully domestic under NIH rules for this opportunity.
What is the overall takeaway for applicants considering this K22?
This K22 is a career transition mechanism intended to help postdoctoral researchers move into independent positions and begin building a sustainable research program. It draws a clear boundary that the candidate cannot lead an independent clinical trial (or related feasibility/ancillary trial studies) under this particular "Independent Clinical Trial Not Allowed" FOA, while still permitting mentored clinical trial experience led by a mentor or co-mentor.
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