Opportunity Information: Apply for RFA MH 24 190
The funding opportunity titled "BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)" (Funding Opportunity Number RFA-MH-24-190) is a National Institutes of Health (NIH) discretionary grant announcement under the NIH BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies). It is a reissue of an earlier announcement (RFA-MH-21-205) and was updated specifically to comply with NIH data management and sharing (DMS) policy requirements. The overall purpose is to support research that directly tackles major ethical questions arising from rapid advances in human brain science and neurotechnology, especially the kinds of cutting-edge tools and approaches being developed and used across the BRAIN Initiative.
This NOFO is positioned as part of a broader set of BRAIN Initiative funding announcements intended to drive transformative progress in understanding human brain function. What makes this particular call distinct is its explicit focus on ethics: it seeks projects that study, anticipate, and help address the ethical implications of emerging neurotechnologies and modern brain research. The announcement is aligned with the BRAIN Initiative scientific roadmap, "BRAIN 2025: A Scientific Vision," and it emphasizes that funded work should ideally complement and integrate with the broader neuroscience breakthroughs supported across BRAIN. In practical terms, applicants are being asked to help ensure that the scientific and technological leaps in brain research are matched by equally rigorous progress in understanding the ethical challenges they create, including how those challenges affect individuals, communities, and society.
The grant mechanism is an R01, meaning it is designed for substantial, hypothesis-driven or conceptually rigorous research programs rather than small pilot studies. The listing notes that clinical trials are optional, which generally means applicants may propose clinical trial activities if they are necessary to answer the ethical research questions, but a clinical trial is not required to be competitive. The opportunity is categorized within the federal "Health, Income Security and Social Services" activity area and is associated with multiple CFDA numbers (93.173, 93.213, 93.242, 93.273, 93.286, 93.853, 93.865, 93.866, 93.867), reflecting its placement within NIH programs and institutes that support neuroscience and mental health related work.
A wide range of organizations are eligible to apply. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other categories. The announcement also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, and non-U.S. entities (foreign organizations). This broad eligibility is consistent with the interdisciplinary nature of neuroethics research, which often benefits from collaborations across academic research, clinical environments, community organizations, legal and policy groups, and international perspectives.
Key administrative details provided in the source include an original closing date of October 11, 2023, and an award ceiling listed at $300,000 (as stated in the extracted data). The posting indicates a creation date of September 1, 2023. While the number of expected awards is not specified in the provided extract, the emphasis of the announcement is clearly on supporting rigorous, ethics-centered research that can keep pace with the accelerating capabilities of neurotechnology and brain science, and that can help guide responsible research practices and societal use of these emerging tools.Apply for RFA MH 24 190
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.213, 93.242, 93.273, 93.286, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2023-09-01.
- Applicants must submit their applications by 2023-10-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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